Permalink to: Bridge the gap

Bridge the gap

We use the quantum mechanics of infrared spectroscopy and the high brightness and non-invasive synchrotron Read More ...

Permalink to: On the Cover of Analytical Chemistry

On the Cover of Analytical Chemistry

IR spectroscopy has long been used to study cells and living tissues, and now the Read More ...

Permalink to: Overview

Overview

The BSISB Program Imaging Technologies at a Glance Download the handout overview (PDF) BSISB develops facilities, Read More ...

To Speed Discovery, Infrared Microscopy Goes “Off the Grid”

E.A. Holman, Y.S. Fang, L. Chen, M. DeWeese, H.-Y. N. Holman, and P.W. Sternberg, “Autonomous Read More ...

Studying red algae biominerals to model coastal resilience

Elusive Source for CPR Bacteria Membrane Lipids Revealed

Permalink to: How Dinosaur Blood Vessels Preserve through the Ages Revealed

How Dinosaur Blood Vessels Preserve through the Ages Revealed

Infrared spectromicroscopy coupled with X-ray spectroscopy and X-ray diffraction analysis show evidence that vertebrate blood Read More ...

Microbial Reefs in Fresh Waters

Human Skin Microbiome Changes with Age

First Detailed Microscopy & Spectroscopy Evidence of Ultra-small Bacteria at Lower Size Limit of Life

IR Probes the Microbial Relationship Between Archaea and Bacteria

Deep-sea Oil Plume Enriched in Oil-degrading Bacteria

Visualizing How to Turn Plants into Biofuels

Rock-Dwelling Microbes Detoxify Hexavalent Chromium (Cr(VI))

BSISB

Berkeley Synchrotron Infrared Structural Biology (BSISB) is a national user program at Lawrence Berkeley National Laboratory, centered around special beamlines that use infrared radiation to study live materials and organisms smaller than the eye can see. It is a US DOE BER’s Biological Systems Science Division/Structural Biology Program.

We use infrared radiation beamlines to study live materials and organisms.

Innovations

Synchrotron Infrared Imaging
MicroFluidics

Far-field Imaging	SINS	sFTIR μTomography
Infrared Mass Spectrometry Imaging

Multiplex Chemotyping Microarray

Sciences : Imaging chemistry of living cells in real time

Metabolic screening and phenotyping of engineered cyanobacteria grown in wastewater for converting CO2 to fatty acids and alkanes

Researchers Image Zinnia Cells Down to Nanoscale Potential Aid for Lignocellulosic Biofuel Production

Structural characterization of a mixed-linkage glucan deficient mutant reveals alteration in cellulose microfibril orientation in rice coleoptile mesophyll cell walls

Chemical and Functional Dynamics in Living Cells

Real-Time Tracking the Molecular Evolution of Deep-Sea Bacteria and Hydrocarbon Degradation

Unraveling genome and function of bacterial minority within archaea community in sulfidic subsurface aquifers

Identifying diet-induced advanced glycation endproducts

Molecular Spectroscopy of Living Cells in Real Time

Mid-infrared reflectivity of experimental atheromas

Study Pinpoints Most Active Areas of Reactions on Nanoscale Particles

Infrared Brings to Light Nanoscale Molecular Arrangement

Microbes in Basalt Thrive on Mixed Diet of Toxic Wastes